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Anti-CDC25A PHOSPHO Antibody
Also for CDC25A (NM_001789)
|The antiserum was produced against a synthesized A synthesized peptide derived from human CDC25A around the phosphorylation site of Sersine 75.|
|Human, Mouse, Rat
||WB: 1:500-1:2000; IHC: 1:50-1:200
|Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.|
|The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.
|Homo sapiens cell division cycle 25A (CDC25A), transcript variant 1|
Entrez Gene 993 Human
Entrez Gene 12530 Mouse
Entrez Gene 171102 Rat
|CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene.|
|PhosphataseDruggable Genome Cell cycleProgesterone-mediated oocyte maturation|
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Western blot analysis on HeLa cell lysate using Phospho-CDC25A(Ser75) Antibody.
Immunohistochemical analysis of paraffin-embedded human lung carcinoma using Phospho- CDC25A (Ser75) Antibody.