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Home Antibody All anti-CDC2 antibodies

Anti-CDC2 Antibody E161

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA300309
  • Rabbit Monoclonal Antibody against CDC2 (Clone E161)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC400676) , 20ug
100ul 325 3-7 Days
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WB(1)
IHC(1)
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Also for CDC2 (NM_001786)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues surrounding Tyr15 of human Cdc2 was used as immunogen. The antibody detects Cdc2 without phosphorylation on Tyrosine 15. It does not detect Y15-phosphorylated Cdc2. Predicted to cross-react with bovine, based
Clone NameE161 IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: 1:50; ICC: 1:500; IP: 1:50
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt.

Reference Data

Target NameHomo sapiens cyclin-dependent kinase 1 (CDK1), transcript variant 1
Alternative NameCDC2; CDC28A; P34CDC2
Database LinkNP_001777
FunctionDuring the eukaryotic cell cycle, activation of Cdc2 (Cdk1) kinase regulates the transition into M-phase (1). Cdc2 forms a complex with cyclin B, and activation of this complex is controlled by dephosphorylation of Cdc2 at tyrosine 15 and threonine 14 (2). Phosphorylation at Tyr15 and is carried out by Wee1 and Myt1 protein kinases (3), while Tyr15 dephosphorylation is carried out by the cdc25 phosphatase (4).
Related Pathway
Cell cycle
Hedgehog signaling pathway
TGF Beta Signaling Pathway
Wnt Signaling Pathway

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WB Image
Western blot - Anti-CDK1 antibody [E161]; All lanes : Anti-CDK1 antibody [E161] at 1/1000 dilution.Lane 1 : A431 cell lysate.Lane 2 : HepG2 cell lysate.Lane 3 : SKBR3 cell lysate.Lane 4 : HeLa cell lysate.Lysates/proteins at 10 µg per lane.Predicted band size : 34 kDa.
IHC Image
Immunohistochemistry (Paraffin-embedded sections) - Cdc2 antibody [E161]; Ab32384, at a 1/50 dilution, staining Cdc2 in paraffin embedded human lymphoma tissue sections by Immunohistochemistry.

 

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