OriGene Technologies, Inc.
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
Home Antibody All anti-CDC2 antibodies

Anti-CDC2 Antibody E161


Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
  • Rabbit Monoclonal Antibody against CDC2 (Clone E161)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400676) , 20ug Explanation
100ul $325 3-7 Days
Add to Shopping Cart

OriGene Data

ImmunogenA synthetic peptide corresponding to residues surrounding Tyr15 of human Cdc2 was used as immunogen. The antibody detects Cdc2 without phosphorylation on Tyrosine 15. It does not detect Y15-phosphorylated Cdc2. Predicted to cross-react with bovine, based
Clone NameE161 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: 1:50; ICC: 1:500; IP: 1:50
Predicted MW Explanation 34 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt.

Reference Data

Target NameHomo sapiens cyclin-dependent kinase 1 (CDK1), transcript variant 1
Alternative NameCDC2; CDC28A; P34CDC2
Database LinkNP_001777
Entrez Gene 983 Human
Entrez Gene 12534 Mouse
Entrez Gene 54237 Rat
FunctionDuring the eukaryotic cell cycle, activation of Cdc2 (Cdk1) kinase regulates the transition into M-phase (1). Cdc2 forms a complex with cyclin B, and activation of this complex is controlled by dephosphorylation of Cdc2 at tyrosine 15 and threonine 14 (2). Phosphorylation at Tyr15 and is carried out by Wee1 and Myt1 protein kinases (3), while Tyr15 dephosphorylation is carried out by the cdc25 phosphatase (4).
Related PathwayProtein KinaseStem cell - PluripotencyDruggable Genome Cell cycleOocyte meiosisp53 signaling pathwayGap junctionProgesterone-mediated oocyte maturation

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - Anti-CDK1 antibody [E161]; All lanes : Anti-CDK1 antibody [E161] at 1/1000 dilution.Lane 1 : A431 cell lysate.Lane 2 : HepG2 cell lysate.Lane 3 : SKBR3 cell lysate.Lane 4 : HeLa cell lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 34 kDa.
Immunohistochemistry (Paraffin-embedded sections) - Cdc2 antibody [E161]; Ab32384, at a 1/50 dilution, staining Cdc2 in paraffin embedded human lymphoma tissue sections by Immunohistochemistry.


Inc 5000 Healthcare Company
All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title