OriGene Technologies, Inc.
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-CD79A antibodies

Anti-CD79A Antibody EP3618

div

Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307506
  • Rabbit monoclonal antibody against CD79a/mb-1 (clone EP3618 )
  • FREE positive control: HEK293T cell transient overexpression lysate (LC400674) , 20ug
100ul $325 3-7 Days
Add to Shopping Cart
WB(1)
IHC(11)
FC(1)
Assay(1)
spacer
Also for CD79A (NM_001783)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide derived from the extracellular region of human CD79a protein.
Clone NameEP3618 IsotypeTissue culture supernatant
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, ASSAY, IHC, FC Suggested DilutionsWB: 1:5000 - 1:20000; IHC-P: 1:100 - 1:250; FC: 1:140
BufferDoes not react with Mouse, Rat. Is unsuitable for ICC or IP.
Purification PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for ICC or IP.

Reference Data

Target NameHomo sapiens CD79a molecule, immunoglobulin-associated alpha (CD79A), transcript variant 1
Alternative NameIGA; MB-1
Database LinkNP_001774
FunctionCD79a (mb-1/ B lymphocyte-specific MB-1 protein) was originally identified on the basis of its restricted expression in lymphocytes of B lineage (1). CD79a associates with surface IgM-receptors; it has been implicated in the signal transduction pathways and in the regulation of type of type 2A-related serine/threonine phosphatases catalytic activity (2). A disulphide-linked heterodimer, consisting of CD79a (mb-1) and CD79b / B29 polypeptides, non-covalently associates with membrane-bound immunoglobulins on B cells to constitute the B cell Ag receptor. CD79 is required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also CD79 interacts with and increases activity of some Src-family tyrosine kinases. (3).
Related Pathway

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - CD79a antibody [EP3618]; All lanes : Anti-CD79a antibody [EP3618] at 1/10000 dilution.Lane 1 : Raji cell lysate.Lane 2 : Daudi cell lysate.Lane 3 : Human tonsil tissue lysate.Lane 4 : Human spleen tissue lysate.Lysates/proteins at 10 µg per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 25 kDa.Observed band size : 44-48 kDa .
Assay Image
Other-Anti-CD79a antibody [EP3618](TA307506); Equilibrium disassociation constant (KD)..
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - CD79a antibody [EP3618]; TA307506 at 1/100 dilution staining CD79a in paraffin-embedded human tonsil tissue by Immunohistochemistry.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-CD79a antibody [EP3618](TA307506); TA307506 showing positive staining in Normal spleen tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-CD79a antibody [EP3618](TA307506); TA307506 showing positive staining in Normal tonsil tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-CD79a antibody [EP3618](TA307506); TA307506 showing negative staining in Normal brain tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-CD79a antibody [EP3618](TA307506); TA307506 showing negative staining in Normal colon tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-CD79a antibody [EP3618](TA307506); TA307506 showing negative staining in Normal heart tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-CD79a antibody [EP3618](TA307506); TA307506 showing negative staining in Normal brain tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-CD79a antibody [EP3618](TA307506); TA307506 showing positive staining in Normal tonsil tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-CD79a antibody [EP3618](TA307506); TA307506 showing negative staining in Normal colon tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-CD79a antibody [EP3618](TA307506); TA307506 showing negative staining in Normal heart tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-CD79a antibody [EP3618](TA307506); TA307506 showing positive staining in Normal spleen tissue.
FC Image
Flow Cytometry - CD79a antibody [EP3618]; Flow cytometric analysis of Raji cells using TA307506 at a 1/140 dilution (red) or a rabbit IgG (negative) (green).

 

spacer
Inc 5000 Healthcare Company Copyright © 2014 OriGene Technologies, Inc. All Rights Reserved. Legal Notices.
9620 Medical Center Dr., Suite 200, Rockville, MD 20850 • 1.888.267.4436

Reproduction of any materials from this website is strictly forbidden without permission.

All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title