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Home Antibody All anti-CD68 antibodies

Anti-CD68 TRUEMAB Antibody Clone OTI3B6

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA802949 CD68 mouse monoclonal antibody, clone OTI3B6 (formerly 3B6) 100ul $325 In Stock
LC420047 CD68 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF802949 Carrier-free (BSA/glycerol-free) CD68 mouse monoclonal antibody, clone OTI3B6 (formerly 3B6) 100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type
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WB(1)
IHC(5)
FC(1)

OriGene Data

ImmunogenHuman recombinant protein fragment corresponding to amino acids 22-319 of human CD68 (NP_001242)produced in SF9 cell.
Clone NameClone OTI3B6 IsotypeIgG1
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application *WB, IHC, FC Suggested Dilutions WB 1:2000, IHC 1:150,
Predicted MW Explanation 37.2 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens CD68 molecule (CD68), transcript variant 1
Alternative NameGP110; LAMP4; SCARD1
Database LinkNP_001242
Entrez Gene 968 Human
FunctionThis gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008].
Related PathwayTransmembraneDruggable Genome Lysosome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CD68 (RC200392, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CD68.
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Immunohistochemical staining of paraffin-embedded Human liver tissue within the normal limits using anti-CD68 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA802949)
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Immunohistochemical staining of paraffin-embedded Carcinoma of Human liver tissue using anti-CD68 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA802949)
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Immunohistochemical staining of paraffin-embedded Human lung tissue within the normal limits using anti-CD68 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA802949)
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Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-CD68 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA802949)
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Immunohistochemical staining of paraffin-embedded Human bladder tissue within the normal limits using anti-CD68 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA802949)
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Flow cytometric Analysis of Uacc257 cells, using anti-CD68 antibody(TA802949),(Red), compared to a nonspecific negative control antibody(TA50011),(Blue). Dilution: 1:50
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