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Home Antibody All anti-CD5 antibodies

Anti-CD5 TRUEMAB Antibody Clone OTI6F7

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA501334 anti-CD5 mouse monoclonal antibody, clone OTI6F7 (formerly 6F7) 100ul $325 In Stock
LC415443 CD5 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF501334 Carrier-free (BSA/glycerol-free) CD5 mouse monoclonal antibody, clone OTI6F7 (formerly 6F7) 100ug $450 3-4 weeks
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WB(2)
FC(1)

OriGene Data

ImmunogenFull length human recombinant protein of human CD5 (NP_055022) produced in HEK293T cell.
Clone NameClone OTI6F7 IsotypeIgG1
Species ReactivityHuman, Monkey Concentration0.96 mg/ml
Guaranteed Application *WB, FC Suggested DilutionsWB 1:500~2000, FLOW 1:100
Predicted MW Explanation 54.4 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens CD5 molecule (CD5)
Alternative NameLEU1; T1
Database LinkNP_055022
Entrez Gene 921 Human
Entrez Gene 695249 Monkey
FunctionCD5 (Lymphocyte antigen T1/Leu-1) is a transmembrane glycoprotein which has been implicated as a receptor in the regulation of T-cell proliferation (1). CD5 is part of the scavenger receptor cysteine-rich (SRCR) family group B and it is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. CD5 is expressed by T cell leukemia, lymphomas, and activated T cells. Occasionally, CD5 antigen is also expressed on a subset of B cells. Mantle cell lymphomas (same as diffuse centrocytic lymphomas) are CD5+ while the follicle center cell lymphomas are CD5. A ligand for CD72/LYB-2, CD5 has been linked to negative regulation of T cell and B cell receptors signaling (2).
Related PathwayTransmembraneDruggable Genome Hematopoietic cell lineage

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CD5 (RC206494, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CD5.
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Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-CD5 monoclonal antibody.
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HEK293T cells transfected with either RC206494 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-CD5 antibody(TA501334), and then analyzed by flow cytometry.
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