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UltraMAB

CD44 UltraMAB Antibody, Clone UMAB133

UltraMAB™ Antibodies - Validated with 10K Protein Chip

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Specifications Citations (0) Related Products Product Documents
SKU Description Datasheet Price Availability*  
UM500098
  • CD44 mouse monoclonal antibody,clone UMAB133, 100 ul
$468 In Stock Add to Shopping Cart
UM570098
  • CD44 mouse monoclonal antibody,clone UMAB133, 30 ul
$120 In Stock Add to Shopping Cart
WB(3)
Data Img
IHC(12)
Data Img

OriGene Data

ImmunogenFull length human recombinant protein of human CD44(NP_000601) produced in HEK293T cell.
Clone NameClone UMAB133 IsotypeIgG1
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IHC Suggested Dilutions WB 1:4000, IHC 1:100,
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens CD44 molecule (Indian blood group) (CD44), transcript variant 1
Alternative NameCDW44; CSPG8; ECMR-III; HCELL; HUTCH-I; IN; LHR; MC56; MDU2; MDU3; MIC4; Pgp1
Database LinkNP_000601
FunctionThe protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq, Jul 2008].
Related Pathway

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of  U251 cell lysate (35ug) by using anti-CD44 monoclonal antibody.
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Western blot analysis of  SF295 cell lysate (35ug) by using anti-CD44 monoclonal antibody.
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Western blot analysis of  MDA-MB231 cell lysate (35ug) by using anti-CD44 monoclonal antibody.
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Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-CD44 mouse monoclonal antibody. (UM500098; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)
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Immunohistochemical staining of paraffin-embedded Human colon tissue using anti-CD44 mouse monoclonal antibody. (UM500098; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)
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Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-CD44 mouse monoclonal antibody. (UM500098; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)
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Immunohistochemical staining of paraffin-embedded Human Kidney tissue using anti-CD44 mouse monoclonal antibody. (UM500098; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)
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Immunohistochemical staining of paraffin-embedded Human lung tissue using anti-CD44 mouse monoclonal antibody. (UM500098; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)
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Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-CD44mouse monoclonal antibody. (UM500098; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)
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Immunohistochemical staining of paraffin-embedded Human pancreas tissue using anti-CD44 mouse monoclonal antibody. (UM500098; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)
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Immunohistochemical staining of paraffin-embedded Carcinoma of Human pancreas tissue using anti-CD44 mouse monoclonal antibody. (UM500098; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)
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Immunohistochemical staining of paraffin-embedded Human thyroid tissue using anti-CD44 mouse monoclonal antibody. (UM500098; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)
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Immunohistochemical staining of paraffin-embedded Carcinoma of Human thyroid tissue using anti-CD44 mouse monoclonal antibody. (UM500098; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)
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Immunohistochemical staining of paraffin-embedded Carcinoma of Human prostate tissue using anti-CD44 mouse monoclonal antibody. (UM500098; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)
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Immunohistochemical staining of paraffin-embedded of human skin using anti-CD44 clone UMAB133 mouse monoclonal antibody at 1:200 dilution and detection with Polink2 Broad HRP DAB. UM500098 requires heat-induced epitope retrieval with citrate pH6.0 at 95-100C 20 minutes. The composit image of (A) skin dermis and (B)sweat gland labeled shows strong membranous and cytoplasmic staining in >95 % of tumor cells and image A and B shows <10% nuclear stain.
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