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Anti-CD4 Antibody EPR3155(2)


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SKU Description Amount Price Availability*  
  • Rabbit monoclonal antibody against CD4(clone EPR3155(2))
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400209) , 20ug Explanation
100ul $325 3-7 Days
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human CD4 was used as an immunogen.
Clone NameEPR3155(2) IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:1000 - 1:10000; IP: 1:10 - 1:100; ICC: 1:500 - 1:1000
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt or IHC-P.

Reference Data

Target NameHomo sapiens CD4 molecule (CD4), transcript variant 1
Alternative NameCD4mut
Database LinkNP_000607
Entrez Gene 920 Human
FunctionT-cell surface glycoprotein CD4 (CD4) is an accessory protein for MHC class-II antigen/T-cell receptor interaction. It is reported that CD4 regulates T-cell activation and induces the aggregation of lipid rafts. CD4 associates with LCK, binds to HIV-1 gp120 and to P4HB/PDI, and upon HIV-1 binding to the cell membrane, it is part of the P4HB/PDI-CD4-CXCR4-gp120 complex. Cell surface expression of CD4 is down-modulated by HIV-1 Envelope polyprotein gp160, which interacts with and sequesters CD4 in the endoplasmic reticulum (1).
Related PathwayES Cell Differentiation/IPSTransmembraneAdult stem cellsInduced pluripotent stem cellsDruggable Genome Cell adhesion molecules (CAMs)Antigen processing and presentationHematopoietic cell lineageT cell receptor signaling pathwayPrimary immunodeficiency

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - CD4 antibody [EPR3155(2)]; All lanes : Anti-CD4 antibody [EPR3155(2)] at 1/1000 dilution.Lane 1 : Human fetal thymus lysate.Lane 2 : Human tonsil lysate.Lane 3 : PBMC lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 51 kDa.


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