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Home All anti-CD4 antibodies
Anti-CD4 Antibody EPR3942
TrueMAB™ Antibodies - Made against Authentic Protein Antigens
* Buy one primary antibody, get 50% off a GAPDH loading control antibody.
OriGene Data
| A synthetic peptide corresponding to residues near the N-terminus of human CD4 was used as an immunogen. |
| EPR3942 |
Rabbit IgG |
| Human |
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| WB |
ICC: 1:50 - 100, WB: 1:1,000 - 10,000, |
| Store at -20C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| (Protein A or G Sepharose) |
Reference Data
| Homo sapiens CD4 molecule (CD4), transcript variant 1 |
| CD4mut |
| NP_000607 |
| T-cell surface glycoprotein CD4 (CD4) is an accessory protein for MHC class-II antigen/T-cell receptor interaction. It is said to possibly regulate T-cell activation and induce the aggregation of lipid rafts. CD4 associates with LCK, binds to HIV-1 gp120 and to P4HB/PDI, and upon HIV-1 binding to the cell membrane, it is part of the P4HB/PDI-CD4-CXCR4-gp120 complex. The subcellular location of CD4 is in the cell membrane; it is a single-pass type I membrane protein that localizes to lipid rafts. Cell surface expression of CD4 is down-modulated by HIV-1 Envelope polyprotein gp160, which interacts with and sequesters CD4 in the endoplasmic reticulum (1). |
Hematopoietic cell lineage |
* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.
WB Image
Western blot analysis on (A) human tonsil, (B) fetal thymus, (C) HuT-78, and (D) Peripheral Blood Mononuclear Cell (PBMC) lysates using anti-CD4 RabMAb .
Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:
- HRP
- Biotin
- PE
- FITC
- DyLight® 488
- DyLight® 550
- DyLight® 594
- DyLight® 633
* DyLight is a trademark of Thermo-Fisher Scientific
Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.
Contact us with your conjugation/bulk request: antibody@origene.com or 888-267-4436 (Tech Support)
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