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Anti-CD38 Antibody EPR4106
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Also for CD38 (NM_001775)
|A synthetic peptide corresponding to residues on the C-terminus of human CD38 was used as an immunogen.|
|Human (Does not react with: Mouse, Rat)
||Lot dependent; please refer to CoA along with shipment
|WB, Assay, IHC, FC
||WB: 1:1000 - 1:10000; IHC-P: 1:100 - 1:250; ICC: 1:100 - 1:250; FC: 1:10 - 1:100
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Is unsuitable for IP.
|Homo sapiens CD38 molecule (CD38), transcript variant 1|
|ADPRC 1; T10|
Entrez Gene 952 Human
|CD38, also called ADP-ribosyl cyclase, is an ectoenzyme that uses nicotinamide adenine dinucleotide (NAD) as a substrate to generate second messengers (1, 2). In particular, it synthesizes cyclic ADP-ribose, a second messenger for glucose-induced insulin secretion (2). CD38 also has cADPr hydrolase activity (2). It is preferentially expressed at both early and late stages of B and T-cell maturation (2). CD38 regulates inflammatory responses by modulating the activity of the responding leukocytes and by altering the activity of non-hematopoietic cells in inflamed tissue (3). CD38 also functions in cell adhesion, signal transduction, and calcium signaling (4). It is expressed at high levels in the pancreas, liver, kidney, malignant lymphoma and neuroblastoma (2).|
|ES Cell Differentiation/IPSTransmembraneCancer stem cellsInduced pluripotent stem cellsDruggable Genome Nicotinate and nicotinamide metabolismMetabolic pathwaysCalcium signaling pathwayHematopoietic cell lineage|
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Western blot - CD38 antibody [EPR4106]; All lanes : Anti-CD38 antibody [EPR4106] at 1/1000 dilution.Lane 1 : HeLa cell lysate.Lane 2 : Human plasma cell lysate.Lane 3 : THP-1 cell lysate.Lane 4 : HuT-78 cell lysate.Lane 5 : fetal thymus cell lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 34 kDa.Observed band size : 45 kDa .
Other-Anti-CD38 antibody [EPR4106](TA307510); Equilibrium disassociation constant (KD)..
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - CD38 antibody [EPR4106]; TA307510, at a dilution of 1/100, staining CD38 in paraffin embedded Human endometrial adenocarcinoma tissue by Immunohistochemistry.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - CD38 antibody [EPR4106]; TA307510, at a dilution of 1/100, staining CD38 in paraffin embedded Human tonsil tissue by Immunohistochemistry.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-CD38 antibody [EPR4106](TA307510); TA307510 showing positive staining in Lymph node tissue.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-CD38 antibody [EPR4106](TA307510); TA307510 showing positive staining in Normal colon tissue.
Flow Cytometry - CD38 antibody [EPR4106]; Flow cytometric analysis of CD38 in HuT-78 cells, using TA307510 (red) at a 1/10 diulution, or a Rabbit IgG (negative) (green).