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Anti-CD30 Antibody EPR4102
Also for CD30 (NM_001243)
|A synthetic peptide corresponding to residues at the C-terminus of human CD30 was used as an immunogen.|
||Tissue culture supernatant
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:1000 - 1:10000; IHC-P: 1:1000 - 1:2000
|Does not react with Mouse, Rat. Is unsuitable for Flow Cyt,ICC or IP.|
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA (Protein A or G Sepharose)
|Is unsuitable for Flow Cyt,ICC or IP.
|Homo sapiens tumor necrosis factor receptor superfamily, member 8 (TNFRSF8), transcript variant 1|
|CD30; D1S166E; Ki-1|
|CD30, TNF-receptor superfamily member, is a receptor for TNFSF8/CD30L. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity (1). |
Cytokine-cytokine receptor interaction
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Western blot - Anti-CD30 antibody [EPR4102]; All lanes : Anti-CD30 antibody [EPR4102] at 1/1000 dilution.Lane 1 : Molt-4 cell lysate.Lane 2 : A431 cell lysate.Lane 3 : HeLa cell lysate.Lysates/proteins at 10 µg per lane.Secondary.HRP labelled Goat anti-rabbit at 1/2000 dilution.Predicted band size : 64 kDa.Observed band size : 120 kDa .
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD30 antibody [EPR4102]; Immunohistochemical analysis of paraffin embedded Human Hodgkin's lymphoma tissue labelling CD30 with ab134080 antibody at a dilution of 1/1000.