Home Antibody All anti-CD274 antibodies
Also for CD274 (NM_014143)
| Peptide with sequence CKKQSDTHLEET, from the C Terminus of the protein sequence according to NP_054862.1.|
|Test: Human. Expected from seq similarity: Human
||ELISA: 1:32,000; WB: 0.3-1 ug/ml; IHC: 4-6 ug/ml
|Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.|
| Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
|In paraffin embedded Human Placenta shows membranous staining of cytotrophoblasts
|Homo sapiens CD274 molecule (CD274), transcript variant 1|
|B7-H; B7H1; PD-L1; PDCD1L1; PDCD1LG1; PDL1|
Entrez Gene 29126 Human
|Involved in the costimulatory signal, essential for T lymphocyte proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibit T-cell proliferation and cytokine production|
|TransmembraneDruggable Genome Cell adhesion molecules (CAMs)|
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TA302988 (0.3µg/ml) staining of Human placenta lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.chemiluminescence.
TA302988 (4µg/ml) staining of paraffin embedded Human Placenta. Steamed antigen retrieval with Tris/EDTA buffer pH 9, HRP-staining.