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Home Antibody All anti-CD274 antibodies

Anti-CD274 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA302988
  • Goat Polyclonal Antibody against PD-L1 / CD274
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC415473) , 20ug Explanation
100ug 325 Next Day
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WB(1)
IHC(1)
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Also for CD274 (NM_014143)
cDNA Clone shRNA/siRNA Primer Pair Protein Antibody

OriGene Data

Immunogen Peptide with sequence CKKQSDTHLEET, from the C Terminus of the protein sequence according to NP_054862.1.
Clone Name IsotypeGoat IgG
Species ReactivityTest: Human. Expected from seq similarity: Human Concentration0.5mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsELISA: 1:32,000; WB: 0.3-1 ug/ml; IHC: 4-6 ug/ml
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Note In paraffin embedded Human Placenta shows membranous staining of cytotrophoblasts

Reference Data

Target NameHomo sapiens CD274 molecule (CD274), transcript variant 1
Alternative NameB7-H; B7H1; PD-L1; PDCD1L1; PDCD1LG1; PDL1
Database LinkNP_054862
Entrez Gene 29126 Human
FunctionInvolved in the costimulatory signal, essential for T lymphocyte proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibit T-cell proliferation and cytokine production
Related PathwayTransmembraneDruggable Genome Cell adhesion molecules (CAMs)

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
TA302988 (0.3µg/ml) staining of Human placenta lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.chemiluminescence.
IHC Image
TA302988 (4µg/ml) staining of paraffin embedded Human Placenta. Steamed antigen retrieval with Tris/EDTA buffer pH 9, HRP-staining.

 

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