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Home Antibody All anti-CD27 antibodies

Anti-CD27 Antibody EPR8568

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310268
  • Rabbit Monoclonal antibody against CD27
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400496) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
IF(1)
Assay(1)
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Also for CD27 (NM_001242)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in the extracellular domain of human CD27 was used as an immunogen.
Clone NameEPR8568 IsotypeTissue culture supernatant
Species ReactivityRat, Human (Does not react with: Mouse) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, ASSAY, IF Suggested DilutionsWB: 1:1000 - 1:10000; FC: 1:10 - 1:100; ICC/IF: 1:50 - 1:100
BufferDoes not react with Mouse. Is unsuitable for IHC-P or IP.
Purification pH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Note Is unsuitable for IHC-P or IP.

Reference Data

Target NameHomo sapiens CD27 molecule (CD27)
Alternative NameS152; S152. LPFS2; T14; TNFRSF7; Tp55
Database LinkNP_001233
Entrez Gene 939 Human
Entrez Gene 500318 Rat
FunctionCD27 is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. CD27 transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor (1).
Related PathwayTransmembraneDruggable Genome Cytokine-cytokine receptor interaction

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-CD27 antibody [EPR8568]; Anti-CD27 antibody [EPR8568] at 1/1000 dilution + Ramos cell lysate at 10 ug.Secondary.Goat anti-rabbit HRP conjugated antibody at 1/2000 dilution.Predicted band size : 29 kDa.
Assay Image
Other-Anti-CD27 antibody [EPR8568](TA310268); Equilibrium disassociation constant (KD)..
IF Image
Immunocytochemistry/ Immunofluorescence - Anti-CD27 antibody [EPR8568]; Immunofluorescent staining of CD27 in Ramos cells, using TA310268 at a 1/50 dilution.

 

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