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Anti-CD27 Antibody EPR8568
Also for CD27 (NM_001242)
|A synthetic peptide corresponding to residues in the extracellular domain of human CD27 was used as an immunogen.|
||Tissue culture supernatant
|Rat, Human (Does not react with: Mouse)
||Lot dependent; please refer to CoA along with shipment
|WB, ASSAY, IF
||WB: 1:1000 - 1:10000; FC: 1:10 - 1:100; ICC/IF: 1:50 - 1:100
|pH: 7.20; Preservative: 0.01% Sodium azide; Constituents: 49% PBS, 50% Glycerol, 0.05% BSA|
|Is unsuitable for IHC-P or IP.
|Homo sapiens CD27 molecule (CD27)|
|S152; S152. LPFS2; T14; TNFRSF7; Tp55|
Entrez Gene 939 Human
Entrez Gene 500318 Rat
|CD27 is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. CD27 transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor (1).|
|TransmembraneDruggable Genome Cytokine-cytokine receptor interaction|
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Western blot - Anti-CD27 antibody [EPR8568]; Anti-CD27 antibody [EPR8568] at 1/1000 dilution + Ramos cell lysate at 10 ug.Secondary.Goat anti-rabbit HRP conjugated antibody at 1/2000 dilution.Predicted band size : 29 kDa.
Other-Anti-CD27 antibody [EPR8568](TA310268); Equilibrium disassociation constant (KD)..
Immunocytochemistry/ Immunofluorescence - Anti-CD27 antibody [EPR8568]; Immunofluorescent staining of CD27 in Ramos cells, using TA310268 at a 1/50 dilution.