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Home Antibody All anti-CD25 antibodies

Anti-CD25 Antibody EPR6452

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310265
  • Rabbit Monoclonal antibody against CD25
  • FREE positive control: HEK293T cell transient overexpression lysate (LC424732) , 20ug
100ul $325 3-7 Days
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IHC(5)
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Also for CD25 (NM_000417)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA recombinant protein fragment corresponding to human CD25 was used as an immunogen.
Clone NameEPR6452 IsotypeIgG
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *IHC Suggested DilutionsIP: 1:10 - 1:100; IHC-P: 1:250 - 1:500; ICC: 1:100 - 1:250
BufferpH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Does not react with Mouse, Rat

Reference Data

Target NameHomo sapiens interleukin 2 receptor, alpha (IL2RA)
Alternative NameCD25; IDDM10; IL2R; TCGFR
Database LinkNP_000408
FunctionCD25, or interleukin 2 (IL2) receptor alpha (IL2RA), and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (CD25) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble CD25 has been isolated and determined to result from extracellular proteolyisis. Mutations in CD25 are associated with interleukin 2 receptor alpha deficiency (1).
Related Pathway
Cytokine-cytokine receptor interaction
Hematopoietic cell lineage
Jak-STAT signaling pathway

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IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-IL2 Receptor alpha antibody [EPR6452]; TA310265, at 1/250 dilution, staining IL2 Receptor alpha in paraffin-embedded Human tonsil tissue by Immunohistochemistry.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-IL2 Receptor alpha antibody [EPR6452](TA310265); TA310265 showing positive staining in Hodgkin's lymphoma tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-IL2 Receptor alpha antibody [EPR6452](TA310265); TA310265 showing negative staining in Normal liver tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-IL2 Receptor alpha antibody [EPR6452](TA310265); TA310265 showing positive staining in Normal thymus tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-IL2 Receptor alpha antibody [EPR6452](TA310265); TA310265 showing positive staining in Normal spleen tissue.

 

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