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Home Antibody All anti-CD1C antibodies

Anti-CD1C TRUEMAB Antibody Clone OTI1F4

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA505387 CD1C mouse monoclonal antibody, clone OTI1F4 (formerly 1F4) 100ul $325 In Stock
LC419762 CD1C HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF505387 Carrier-free (BSA/glycerol-free) CD1C mouse monoclonal antibody, clone OTI1F4 (formerly 1F4) 100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type
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WB(2)
IHC(2)
IF(1)

OriGene Data

ImmunogenFull length human recombinant protein of human CD1C(NP_001756) produced in HEK293T cell.
Clone NameClone OTI1F4 IsotypeIgG1
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application *WB, IHC, IF Suggested Dilutions WB 1:500~2000, IHC 1:150, IF 1:100,
Predicted MW Explanation 35.7 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens CD1c molecule (CD1C)
Alternative NameBDCA1; CD1; CD1A; R7
Database LinkNP_001756
Entrez Gene 911 Human
FunctionThis gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail. Alternatively spliced transcript variants of this gene have been observed, but their full-length nature is not known. [provided by RefSeq].
Related PathwayTransmembraneDruggable Genome Hematopoietic cell lineage

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CD1C (RC218490, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CD1C.
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Western blot analysis of extracts (35ug) from 9 different cell lines by usin g anti-CD1C monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).
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Immunohistochemical staining of paraffin-embedded Human lymphoma tissue using anti-CD1C mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA505387)
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Immunohistochemical staining of paraffin-embedded Human tonsil within the normal limits using anti-CD1C mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA505387)
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Anti-CD1C mouse monoclonal antibody (TA505387) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY CD1C(RC218490).
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