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Anti-CD1C TRUEMAB Antibody Clone 2D4
TrueMAB Antibodies - Made against Authentic Protein Antigens
Also for CD1C (NM_001765)
|Full length human recombinant protein of human CD1C(NP_001756) produced in HEK293T cell.|
|WB, IHC, IF
|| WB 1:500~2000, IHC 1:150, IF 1:100,
|PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography
|Homo sapiens CD1c molecule (CD1C)|
|BDCA1; CD1; CD1A; R7|
Entrez Gene 911 Human
|This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail. Alternatively spliced transcript variants of this gene have been observed, but their full-length nature is not known. [provided by RefSeq]. |
|TransmembraneDruggable Genome Hematopoietic cell lineage|
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CD1C (RC218490, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CD1C.
Western blot analysis of extracts (35ug) from 9 different cell lines by usin g anti-CD1C monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).
Immunohistochemical staining of paraffin-embedded Human lymphoma tissue using anti-CD1C mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA505385)
Immunohistochemical staining of paraffin-embedded Human tonsil using anti-CD1C mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA505385)
Anti-CD1C mouse monoclonal antibody (TA505385) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY CD1C(RC218490).