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Home Antibody All anti-CD163 antibodies

Anti-CD163 TRUEMAB Antibody Clone OTI3B4

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA506386 CD163 mouse monoclonal antibody, clone OTI3B4 (formerly 3B4) 100ul $325 In Stock
LC401362 CD163 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF506386 Carrier-free (BSA/glycerol-free) CD163 mouse monoclonal antibody, clone OTI3B4 (formerly 3B4) 100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type
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WB(2)
IHC(1)
IF(1)
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Also for CD163 (NM_004244)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human CD163(NP_004235) produced in HEK293T cell.
Clone NameClone OTI3B4 IsotypeIgG2a
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application *WB, IHC, IF Suggested Dilutions WB 1:200~4000, IHC 1:150, IF 1:100,
Predicted MW Explanation 125.3 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens CD163 molecule (CD163), transcript variant 1
Alternative NameM130; MM130
Database LinkNP_004235
Entrez Gene 9332 Human
FunctionThe protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011].
Related PathwaySecreted ProteinTransmembraneDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CD163 (RC208557, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CD163.
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Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-CD163 monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).
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Immunohistochemical staining of paraffin-embedded Human liver tissue within the normal limits using anti-CD163 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA506386)
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Anti-CD163 mouse monoclonal antibody (TA506386) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY CD163(RC208557).
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