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Home Antibody All anti-CCR5 antibodies

Anti-CCR5 PHOSPHO Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA325319
  • Rabbit Polyclonal CCR5 (Ser336) Antibody (Phospho-specific)
100ul 325 In Stock
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WB(1)

OriGene Data

ImmunogenThe antiserum was produced against A synthesized peptide derived from human CCR5 around the phosphorylation site of Serine 336
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1
Guaranteed Application *WB Suggested DilutionsWB: 1:500-1:2000
BufferRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.

Reference Data

Target NameHomo sapiens chemokine (C-C motif) receptor 5 (gene/pseudogene) (CCR5), transcript variant A
Alternative NameCC-CKR-5; CCCKR5; CCR-5; CD195; CKR-5; CKR5; CMKBR5; IDDM22
Database LinkNP_000570
Entrez Gene 1234 Human
Entrez Gene 12774 Mouse
Entrez Gene 117029 Rat
FunctionCCR5 a 7-transmembrane G-linked receptor for a number of inflammatory C-C type chemokines including MIP-1-alpha, MIP-1-beta and RANTES. Transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Acts as a coreceptor (along with CD4) for HIV-1 R5 isolates. Interacts with PRAF2. Interacts with HIV-1 surface protein gp120.
Related PathwayGPCRES Cell Differentiation/IPSTransmembraneDruggable Genome Cytokine-cytokine receptor interactionChemokine signaling pathwayEndocytosis

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of CCR5 phosphorylation expression in Jurkat whole cell lysates,The lane on the left is treated with the antigen-specific peptide.

 

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