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Anti-CCR5 PHOSPHO Antibody
Also for CCR5 (NM_000579)
|The antiserum was produced against A synthesized peptide derived from human CCR5 around the phosphorylation site of Serine 336|
|Human, Mouse, Rat
|Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.|
|The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.
|Homo sapiens chemokine (C-C motif) receptor 5 (gene/pseudogene) (CCR5), transcript variant A|
|CC-CKR-5; CCCKR5; CCR-5; CD195; CKR-5; CKR5; CMKBR5; IDDM22|
|CCR5 a 7-transmembrane G-linked receptor for a number of inflammatory C-C type chemokines including MIP-1-alpha, MIP-1-beta and RANTES. Transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Acts as a coreceptor (along with CD4) for HIV-1 R5 isolates. Interacts with PRAF2. Interacts with HIV-1 surface protein gp120.|
Cytokine-cytokine receptor interaction
Signaling by GPCR
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Western blot analysis of CCR5 phosphorylation expression in Jurkat whole cell lysates,The lane on the left is treated with the antigen-specific peptide.