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Home Antibody All anti-CBL antibodies

Anti-CBL PHOSPHO Antibody E160

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310242
  • Rabbit Monoclonal antibody against Cbl, pY774 (CBL) (Phospho-specific)
100ul 325 3-7 Days
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IHC(1)
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Also for CBL (NM_005188)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic phospho-peptide corresponding to residues surrounding Tyr774 of human Cbl was used as immunogen. The antibody detects Cbl phosphorylated on Tyrosine 774.
Clone NameE160 IsotypeIgG
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *IHC Suggested DilutionsWB: 1:1,000; IHC 1:25; ICC: 1:25; IP: 1:20; FC: 1:20;
BufferStore at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.

Reference Data

Target NameHomo sapiens Cbl proto-oncogene, E3 ubiquitin protein ligase (CBL)
Alternative NameC-CBL; CBL2; FRA11B; NSLL; RNF55
Database LinkNP_005179
Functionc-Cbl, product of c-cbl proto-oncogene, is a 120 kDa cytoplasmic protein involved in tyrosine kinase-dependent signaling pathways (1-3). c-Cbl is one of the earliest targets of tyrosine phosphorylation in response to a number of cellular stimuli. For instance, stimulation of growth factor receptors by EGF, PDGF, NGF and FGF, results in c-Cbl tyrosine phosphorylation, in lymphoid and other cell lines (4).
Related Pathway
EGFR1 Signaling Pathway
Jak-STAT signaling pathway

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IHC Image
Immunohistochemical analysis of paraffin-embedded human cervical carcinoma using TA310242 at 1/25 dilution.

 

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