Anti-CAV1 Antibody,

Also for CAV1 (NM_001753)

OriGene Data

Immunogen	Peptide with sequence C-DELSEKQVYDAH, from the internal region of the protein sequence according to NP_001744.2.
Clone Name		Isotype	Goat IgG
Species Reactivity	Human, Mouse, Rat, Dog, porcine	Concentration	0.5 mg/ml
Guaranteed Application *	WB	Suggested Dilutions	ELISA: 1:32,000. WB: 0.3-1µg/ml.
Buffer	Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. (Protein A or G Sepharose)

Reference Data

Target Name	Homo sapiens caveolin 1, caveolae protein, 22kDa (CAV1), transcript variant 1
Alternative Name	BSCL3; CGL3; MSTP085; VIP21
Database Link	NP_001744
Function	The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 MAP kinase cascade. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. By using alternative initiation codons in the same reading frame, two isoforms (alpha and beta) are encoded by a single transcript from this gene. [provided by RefSeq].
Related Pathway	EGFR1 Signaling Pathway Focal Adhesion Hemostasis TGF Beta Signaling Pathway

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WB Image

TA302639 (0.3µg/ml) staining of human spleen lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:

HRP
Biotin
PE
FITC
DyLight® 488
DyLight® 550
DyLight® 594
DyLight® 633

* DyLight is a trademark of Thermo-Fisher Scientific

Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.

Anti-CAV1 Antibody

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

OriGene Data

Reference Data