Home Antibody All anti-CAV1 antibodies
Also for CAV1 (NM_001753)
| Peptide with sequence C-DELSEKQVYDAH, from the internal region of the protein sequence according to NP_001744.2.|
|Test: Human. Expected from seq similarity: Human, Mouse, Rat, Dog, Pig
||ELISA: 1:8,000. WB: 0.01-0.03ug/ml
|Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.|
|Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
|Homo sapiens caveolin 1, caveolae protein, 22kDa (CAV1), transcript variant 1|
|BSCL3; CGL3; LCCNS; MSTP085; PPH3; VIP21|
Entrez Gene 857 Human
Entrez Gene 12389 Mouse
Entrez Gene 25404 Rat
Entrez Gene 403980 Dog
|The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 MAP kinase cascade. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. By using alternative initiation codons in the same reading frame, two isoforms (alpha and beta) are encoded by a single transcript from this gene. [provided by RefSeq]. |
|TransmembraneDruggable Genome Focal adhesionViral myocarditis|
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TA302639 (0.3µg/ml) staining of human spleen lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.