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Anti-CAV1 Antibody E249

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA300391
  • Rabbit Monoclonal Antibody against CAV1 (Clone E249)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC400664) , 20ug
100ul 325 In Stock
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WB(1)
IHC(3)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues near C-terminus of human Caveolin-1 was used as immunogen. The antibody should recognize both alpha and beta form of Caveolin-1.
Clone NameE249 IsotypeIgG fraction
Species ReactivityHuman, Mouse Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IHC Suggested DilutionsICC/IF: Use at an assay dependent dilution; IHC-P: 1:250; ICC: 1:100; WB: 1:1000 - 1:10000
BufferDoes not react with Rat. Is unsuitable for Flow Cyt or IP.
Purification PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt or IP.

Reference Data

Target NameHomo sapiens caveolin 1, caveolae protein, 22kDa (CAV1), transcript variant 1
Alternative NameBSCL3; CGL3; LCCNS; MSTP085; PPH3; VIP21
Database LinkNP_001744
FunctionCaveolins make up a family of proteins that are principal structural components of hairpin-like domains in the plasma membrane (1). It is believed that caveolins serve as scaffolding proteins for the integration of signal transduction. Three members of caveolins (caveolin-1, -2 and -3) have been identified, possessing different tissue distributions (2). Caveolins interact with multiple signaling molecules, such as the G-protein alpha subunit (1), tyrosine kinase receptors, PKCs, Src family tyrosine kinases and eNOS (2,3). Caveolin-1 has been implicated in the pathogenesis of mammary epithelial cell hyperplasia (4).
Related Pathway
EGFR1 Signaling Pathway
Focal Adhesion
Hemostasis
TGF Beta Signaling Pathway

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WB Image
Western blot - Caveolin 1 antibody [E249]; Anti-Caveolin 1 antibody [E249] + A431 cell lysate.Predicted band size : 20 kDa.Observed band size : 23 kDa .Additional bands at : 22 kDa. We are unsure as to the identity of these extra bands.
IHC Image
Immunohistochemistry (Paraffin-embedded sections) - Anti-Caveolin 1 antibody [E249]; Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human urinary bladder tissue, staining Caveolin 1 with TA300391 at 1/250 dilution.
IHC Image
Immunohistochemistry (Paraffin-embedded sections) - Anti-Caveolin 1 antibody [E249]; Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human lung tissue, staining Caveolin 1 with TA300391 at 1/250µg/ml.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Caveolin 1 antibody [E249]; Immunohistochemical analysis of developing Human lung tissue, staining Caveolin 1 with TA300391 at 1/250 dilution.

 

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