Anti-CAT Antibody, clone 3C3

Also for CAT (NM_001752)

OriGene Data

Immunogen	Full length human recombinant protein of human CAT (NP_111743) produced in HEK293T cell.
Clone Name	clone 3C3	Isotype	IgG1
Species Reactivity	Human , Dog	Concentration	0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *	WB, IHC, IF	Suggested Dilutions	WB 1:200~500, IHC 1:150, IF 1:100,
Buffer	PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification	Purified from mouse ascites fluids by affinity chromatography (Protein A or G Sepharose)

Reference Data

Target Name	Homo sapiens catalase (CAT)
Alternative Name	MGC138422; MGC138424
Database Link	NP_001743
Function	This gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer's disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene. [provided by RefSeq].
Related Pathway

* Shipping is in business days

* OriGene provides validated application data and protocol, with money back guarantee.

WB Image

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CAT (RC210763, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CAT.

WB Image

Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-CAT monoclonal antibody.

IHC Image

Immunohistochemical staining of paraffin-embedded Human Kidney tissue using anti-CAT mouse monoclonal antibody. (TA502497)

IHC Image

Immunohistochemical staining of paraffin-embedded Human liver tissue using anti-CAT mouse monoclonal antibody. (TA502497)

IHC Image

Immunohistochemical staining of paraffin-embedded Human lung tissue using anti-CAT mouse monoclonal antibody. (TA502497)

IHC Image

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-CAT mouse monoclonal antibody. (TA502497)

IHC Image

Immunohistochemical staining of paraffin-embedded Human endometrium tissue using anti-CAT mouse monoclonal antibody. (TA502497)

IHC Image

Immunohistochemical staining of paraffin-embedded Human prostate tissue using anti-CAT mouse monoclonal antibody. (TA502497)

IHC Image

Immunohistochemical staining of paraffin-embedded Carcinoma of Human prostate tissue using anti-CAT mouse monoclonal antibody. (TA502497)

IHC Image

Immunohistochemical staining of paraffin-embedded Human lymph node tissue using anti-CAT mouse monoclonal antibody. (TA502497)

IHC Image

Immunohistochemical staining of paraffin-embedded Human lymphoma tissue using anti-CAT mouse monoclonal antibody. (TA502497)

IF Image

Anti-CAT mouse monoclonal antibody (TA502497) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY CAT(RC210763).

Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:

HRP
Biotin
PE
FITC
DyLight® 488
DyLight® 550
DyLight® 594
DyLight® 633

* DyLight is a trademark of Thermo-Fisher Scientific

Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.

Anti-CAT TrueMAB Antibody clone 3C3

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

OriGene Data

Reference Data