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Anti-CASP8 PHOSPHO Antibody
Also for CASP8 (NM_001080124)
|The antiserum was produced against A synthesized peptide derived from human Caspase 8 around the phosphorylation site of Serine 347|
||WB: 1:500-1:2000; IHC: 1:50-1:200
|Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.|
|The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.
|Homo sapiens caspase 8, apoptosis-related cysteine peptidase (CASP8), transcript variant F|
|ALPS2B; CAP4; Casp-8; FLICE; MACH; MCH5|
|This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain, a large protease subunit, and a small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits.|
MAPK signaling pathway
Toll-like receptor signaling pathway
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Western blot analysis of Caspase 8 phosphorylation expression in Jurkat whole cell lysates,The lane on the left is treated with the antigen-specific peptide.