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Home Antibody All anti-CASP7 antibodies

Anti-CASP7 Antibody Y33

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA303418
  • Rabbit monoclonal antibody against Caspase-7 (pro)(Y33)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC409592) , 20ug Explanation
100ul $325 3-7 Days
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WB(1)
IHC(1)
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Also for CASP7 (NM_033339)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to N-terminal residues of human Pro-Caspase-7 was used as immunogen. The antibody only recognizes the pro-form of Caspase-7. It does not react with the cleaved forms (active enzyme) of Caspase-7.
Clone NameY33 IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1,000; IHC: 1:50; ICC: 1:50
Predicted MW Explanation 34 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Does not react with Mouse, Rat

Reference Data

Target NameHomo sapiens caspase 7, apoptosis-related cysteine peptidase (CASP7), transcript variant c
Alternative NameCASP-7; CMH-1; ICE-LAP3; LICE2; MCH3
Database LinkNP_203125
Entrez Gene 840 Human
FunctionThis gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of this caspase is cleaved by caspase 3 and 10. It is activated upon cell death stimuli and induces apoptosis. Alternative splicing results in four transcript variants, encoding three distinct isoforms. [provided by RefSeq].
Related PathwayProteaseDruggable Genome ApoptosisAlzheimer's disease

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - pro Caspase 7 antibody [Y33]; Anti-pro Caspase 7 antibody [Y33] at 1/1000 dilution + Jurkat cell lysate.Predicted band size : 34 kDa.Observed band size : 34 kDa.
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Immunohistochemistry (Paraffin-embedded sections) - pro Caspase 7 antibody [Y33]; Immunohistochemical analysis of paraffin-embedded human lung squamous carcinoma using TA303418 at 1/50 dilution.
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