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Home Antibody All anti-CARD11 antibodies

Anti-CARD11 Antibody EPR3177

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307831
  • Rabbit monoclonal antibody against CARD11(clone EPR3177)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC403162) , 20ug
100ul 325 3-7 Days
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WB(1)
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Also for CARD11 (NM_032415)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues on the C-terminus in human CARD11 was used as an immunogen.
Clone NameEPR3177 IsotypeTissue culture supernatant
Species ReactivityMouse, Human (Does not react with: Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:1000 - 1:10000; ICC/IF: 1:50 - 1:100
BufferDoes not react with Rat. Is unsuitable for Flow Cyt,IHC-P or IP.
Purification PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt,IHC-P or IP.

Reference Data

Target NameHomo sapiens caspase recruitment domain family, member 11 (CARD11)
Alternative NameBENTA; BIMP3; CARMA1; IMD11; PPBL
Database LinkNP_115791
FunctionCARD11 belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. It is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). CARD11 has a domain structure similar to that of CARD14. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, CARD11 activated NF-kappaB and induced the phosphorylation of BCL10.
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - CARD11 antibody [EPR3177]; All lanes : Anti-CARD11 antibody [EPR3177] at 1/1000 dilution.Lane 1 : K562 cell lysates .Lane 2 : Ramos cell lysates .Lysates/proteins at 10 ug per lane.Predicted band size : 133 kDa.Observed band size : 130 kDa .

 

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