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Home Antibody All anti-CAMKK2 antibodies

Anti-CAMKK2 Antibody


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SKU Description Amount Price Availability*  
TA308424 Rabbit polyclonal antibody to CaMKK beta (calcium/calmodulin-dependent protein kinase kinase 2, beta) 100ul $325 In Stock
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OriGene Data

ImmunogenSynthetic peptide corresponding to a region within amino acids 1 and 498 of CaMKK beta
Clone Name IsotypeIgG
Species ReactivityHuman (Predicted: Rat) Concentration0.73mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsIHC:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 55kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Rat (86%)

Reference Data

Target NameHomo sapiens calcium/calmodulin-dependent protein kinase kinase 2, beta (CAMKK2), transcript variant 1
Alternative NameCAMKK; CAMKKB
Database LinkNP_006540
Entrez Gene 10645 Human
Entrez Gene 83506 Rat
FunctionThe product of this gene belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This protein plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. Seven transcript variants encoding six distinct isoforms have been identified for this gene. Additional splice variants have been described but their full-length nature has not been determined. The identified isoforms exhibit a distinct ability to undergo autophosphorylation and to phosphorylate the downstream kinases. [provided by RefSeq]
Related PathwayProtein KinaseTranscription FactorsDruggable Genome Adipocytokine signaling pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

Sample (30 ug of whole cell lysate). A: U87-MG. 10% SDS PAGE. TA308424 diluted at 1:1000.
Immunohistochemical analysis of paraffin-embedded U87 xenograft, using CaMKK beta(TA308424) antibody at 1:500 dilution.


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