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Anti-CACNA1H Antibody S55-10
Also for CACNA1H (NM_001005407)
|Fusion protein amino acids 1019-1293 (II-III loop) of human Cav3.2, accession number O95180|
||WB, IP, ICC
|PBS pH7.4, 50% glycerol|
|Homo sapiens calcium channel, voltage-dependent, T type, alpha 1H subunit (CACNA1H), transcript variant 2|
|CACNA1HB; Cav3.2; ECA6; EIG6|
|This gene encodes a T-type member of the alpha-1 subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. The alpha-1 subunit has 24 transmembrane segments and forms the pore through which ions pass into the cell. There are multiple isoforms of each of the proteins in the complex, either encoded by different genes or the result of alternative splicing of transcripts. Alternate transcriptional splice variants, encoding different isoforms, have been characterized for the gene described here. Studies suggest certain mutations in this gene lead to childhood absence epilepsy (CAE). [provided by RefSeq]. |
MAPK signaling pathway
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IHC analysis of Cav3.2 in frozen sections of mouse brain extract using SMC-303.