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Anti-C1S TRUEMAB Antibody Clone OTI5F2

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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SKU Description Amount Price Availability*  
TA504245 C1S mouse monoclonal antibody, clone OTI5F2 (formerly 5F2) 100ul $325 In Stock
LC400655 C1S HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF504245 Carrier-free (BSA/glycerol-free) C1S mouse monoclonal antibody, clone OTI5F2 (formerly 5F2) 100ug $450 3-4 weeks
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WB(1)
IHC(7)
IF(1)
FC(2)

OriGene Data

ImmunogenFull length human recombinant protein of human C1S(NP_001725) produced in HEK293T cell.
Clone NameClone OTI5F2 IsotypeIgG2a
Species ReactivityHuman Concentration0.71 mg/ml
Guaranteed Application *WB, IHC, IF, FC Suggested DilutionsWB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100,
Predicted MW Explanation 74.8 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens complement component 1, s subcomponent (C1S), transcript variant 2
Alternative NameFLJ44757
Database LinkNP_001725
Entrez Gene 716 Human
FunctionThis gene encodes a serine protease, which is a major constituent of the human complement subcomponent C1. C1s associates with two other complement components C1r and C1q in order to yield the first component of the serum complement system. Defects in this gene are the cause of selective C1s deficiency. [provided by RefSeq].
Related PathwayProteaseDruggable Genome Complement and coagulation cascadesSystemic lupus erythematosus

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY C1S (RC218963, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-C1S.
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Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-C1S mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504245)
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Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-C1S mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504245)
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Immunohistochemical staining of paraffin-embedded Carcinoma of Human kidney tissue using anti-C1S mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504245)
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Immunohistochemical staining of paraffin-embedded Human liver tissue within the normal limits using anti-C1S mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504245)
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Immunohistochemical staining of paraffin-embedded Carcinoma of Human liver tissue using anti-C1S mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504245)
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Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-C1S mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504245)
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Immunohistochemical staining of paraffin-embedded Carcinoma of Human bladder tissue using anti-C1S mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504245)
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Anti-C1S mouse monoclonal antibody (TA504245) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY C1S(RC218963).
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Flow cytometric Analysis of Hela cells, using anti-C1S antibody(TA504245),(Red), compared to a nonspecific negative control antibody,(Blue).
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Flow cytometric Analysis of Jurkat cells, using anti-C1S antibody(TA504245),(Red), compared to a nonspecific negative control antibody,(Blue).
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