Home Antibody All anti-Bin1 antibodies
Also for Bin1 (NM_004305)
|Synthetic peptide corresponding to residues surrounding amino acids 578 of mouse BIN-1|
|Human, mouse, rat
||WB: 0.5-4 ug/ml
|100 µg (0.2mg/ml) immunoaffinity purified rabbit anti-Bin-1 polyclonal antibody in phosphate-buffered saline (PBS) containing 0.1% BSA, 30% glycerol, and 0.01% thimerosal.|
|Homo sapiens bridging integrator 1 (BIN1), transcript variant 8|
|AMPH2; AMPHL; SH3P9|
Entrez Gene 274 Human
Entrez Gene 30948 Mouse
Entrez Gene 117028 Rat
|BIN-1 is a tumor suppressor protein that was identified in a genetic screen for proteins that interact with the MCY oncoprotein. BIN-1 inhibits the oncogenic activity of MYC, possibly through activating or facilitating apoptosis. BIN is a short-lived protein with a half-life of about 2 hours. |
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Western blot analysis of BIN-1 expression in Jurkat cells treated with (Lane 2) or without (Lane 1) camptothecin.