A synthetic phospho-peptide corresponding to residues surrounding Tyrosine 551 of human Btk was used as immunogen. The antibody will detect Btk phosphorylation on Tyrosine 551.
Buffer
50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
Clone Name
EP267Y
Isotype
Rabbit IgG
Species Reactivity
Human
Concentration
Purification
Guaranteed Application *
WB
Suggested Dilutions
WB: 1:2,000 ICC: 1:100-250
Background
The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. [provided by RefSeq].
Related Pathway
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