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Home Antibody All anti-BRAF antibodies

Anti-BRAF TRUEMAB Antibody clone 3C3

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA500458
  • anti-BRAF mouse monoclonal antibody, Clone 3C3
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401382) , 20ug
100ul 325 In Stock
CF500458
  • Carrier-free (BSA/glycerol-free) BRAF mouse monoclonal antibody, Clone 3C3
100ug $450 3-4 weeks
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WB(1)
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Also for BRAF (NM_004333)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFull-length protein expressed in 293T cell transfected with human BRAF expression vector
Clone Nameclone 3C3 IsotypeIgG1
Species ReactivityHuman Concentration1.60mg/ml
Guaranteed Application *WB Suggested DilutionsWB 1:2000
BufferPBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens B-Raf proto-oncogene, serine/threonine kinase (BRAF)
Alternative NameB-RAF1; BRAF1; NS7; RAFB1
Database LinkNP_004324
FunctionThis gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases.This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation,and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma,non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene
Related Pathway
Focal Adhesion
MAPK signaling pathway
Senescence and Autophagy

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY BRAF (RC211013, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-BRAF.

 

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