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Home Antibody All anti-BMPR2 antibodies

Anti-BMPR2 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308587
  • Rabbit polyclonal antibody to BMPR2 (bone morphogenetic protein receptor, type II (serine/threonine kinase))
  • FREE positive control: HEK293T cell transient overexpression lysate (LC420077) , 20ug
100ul $325 In Stock
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Also for BMPR2 (NM_001204)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenRecombinant protein fragment contain a sequence corresponding to a region within amino acids 667 and 921 of Human BMPR2
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse Concentration0.89mg/ml
Guaranteed Application *WB Suggested DilutionsWB:1:500-1:3000;
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens bone morphogenetic protein receptor, type II (serine/threonine kinase) (BMPR2)
Alternative NameBMPR-II; BMPR3; BMR2; BRK-3; POVD1; PPH1; T-ALK
Database LinkNP_001195
FunctionThis gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease. [provided by RefSeq]
Related Pathway
Cytokine-cytokine receptor interaction
TGF Beta Signaling Pathway

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WB Image
Sample(30 ug of whole cell lysate) A:H1299 B:Raji (anti-BMPR2 antibody diluted at 1:1000)

 

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