The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMP's are part of the transforming growth factor-beta (TGFB) superfamily. BMP's were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, BMP7 has a proposed role in early development and possible bone inductive activity (1).
Cytokine-cytokine receptor interaction
Hedgehog signaling pathway
TGF Beta Signaling Pathway
* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.