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Home Antibody All anti-BIRC7 antibodies

Anti-BIRC7 TRUEMAB Antibody Clone OTI1D12

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA500758 anti-BIRC7 (Livin) mouse monoclonal antibody, clone OTI1D12 (formerly 1D12) 100ul
30ul
$325 In Stock
LC403386 BIRC7 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF500758 Carrier-free (BSA/glycerol-free) BIRC7 mouse monoclonal antibody, clone OTI1D12 (formerly 1D12) 100ug $450 4 Weeks
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WB(3)
IHC(1)
FC(2)
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Also for BIRC7 (NM_139317)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human BIRC7 (NP_071444) produced in HEK293T cell.
Clone NameClone OTI1D12 IsotypeIgG1
Species ReactivityHuman Concentration0.36 mg/ml
Guaranteed Application *WB, IHC, FC Suggested DilutionsWB 1:1000, IHC 1:50, Flow 1:100
Predicted MW Explanation 32.8 kDa
BufferPBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens baculoviral IAP repeat containing 7 (BIRC7), transcript variant 1
Alternative NameKIAP; LIVIN; ML-IAP; MLIAP; RNF50
Database LinkNP_647478
Entrez Gene 79444 Human
FunctionThe protein encoded by this gene is a member of the family of inhibitor of apoptosis proteins (IAP) and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Two transcript variants encoding different isoforms have been found for this gene. The two isoforms have different antiapoptotic properties, with isoform alpha protecting cells from apoptosis induced by staurosporine and isoform b protecting cells from apoptosis induced by etoposide.
Related PathwayDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.


WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY BIRC7 (RC204906, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-BIRC7.
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WB Image
Western blot analysis of extracts (10ug) from a mouse cell line and 3 different mouse tissues by using anti-BIRC7 monoclonal antibody.(1:200)
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WB Image
Western blot analysis of extracts (10ug) from 10 Human tissue by using anti-BIRC7 monoclonal antibody at 1:200 (1: Testis; 2: Omentum; 3: Uterus; 4: Breast; 5: Brain; 6: Liver; 7: Ovary; 8: Thyroid gland; 9: colon;10: spleen).
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IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of liver tissue using anti-BIRC7mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500758, Dilution 1:50)
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FC Image
Flow cytometric analysis of Hela cells, using anti-BIRC7 antibody(TA500758),(Red) compared to a nonspecific negative control antibody(TA50011)(Blue).
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FC Image
Flow cytometric analysis of Jurkat cells, using anti-BIRC7 antibody(TA500758),(Red) compared to a nonspecific negative control antibody(TA50011)(Blue).
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