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Home Antibody All anti-BIRC7 antibodies

Anti-BIRC7 Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA322202 Anti-BIRC7 Rabbit Polyclonal Antibody 100ul $325 2-3 Weeks
LC411731 BIRC7 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)
IHC(1)
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Also for BIRC7 (NM_022161)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenFull length fusion protein
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.8mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsELISA: 1:1000-5000, WB: 1:200-1000, IHC: 1:20-50
Predicted MW Explanation 33kDa
BufferPBS pH7.3, 0.05% NaN3, 50% glycerol
Purification Antigen affinity purification

Reference Data

Target NameHomo sapiens baculoviral IAP repeat containing 7 (BIRC7), transcript variant 2
Alternative NameKIAP; LIVIN; ML-IAP; MLIAP; RNF50
Database LinkNP_071444
Entrez Gene 79444 Human
Entrez Gene 329581 Mouse
Entrez Gene 296468 Rat
FunctionThe protein encoded by this gene is a member of the family of inhibitor of apoptosis proteins (IAP) and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases; while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Two transcript variants encoding different isoforms have been found for this gene. The two isoforms have different antiapoptotic properties; with isoform alpha protecting cells from apoptosis induced by staurosporine and isoform b protecting cells from apoptosis induced by etoposide.?
Related PathwayDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of Human fetal brain tissue using TA322202(BIRC7 Antibody) at dilution 1/400
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Immunohistochemistry of paraffin-embedded Human colon cancer tissue using TA322202(BIRC7 Antibody)(left image) at dilution 1/20, the image on the right is treated with the fusion protein.(Original magnification: x200)
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