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Home Antibody All anti-BIRC7 antibodies

Anti-BIRC7 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308543
  • Rabbit polyclonal antibody to ML-IAP (baculoviral IAP repeat-containing 7)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC411731) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
IHC(1)
IF(1)
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Also for BIRC7 (NM_022161)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 1 and 241 of Livin (Uniprot ID#Q96CA5)
Clone Name IsotypeIgG
Species ReactivityHuman Concentration0.98mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 33kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens baculoviral IAP repeat containing 7 (BIRC7), transcript variant 2
Alternative NameKIAP; LIVIN; ML-IAP; MLIAP; RNF50
Database LinkNP_071444
Entrez Gene 79444 Human
FunctionThe protein encoded by this gene is a member of the family of inhibitor of apoptosis proteins (IAP) and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Two transcript variants encoding different isoforms have been found for this gene. The two isoforms have different antiapoptotic properties, with isoform alpha protecting cells from apoptosis induced by staurosporine and isoform b protecting cells from apoptosis induced by etoposide. [provided by RefSeq]
Related PathwayDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Livin antibody detects BIRC7 protein by Western blot analysis. A. 30 ug 293T whole cell lysate/extract. B. 30 ug A431 whole cell lysate/extract. C. 30 ug HepG2 whole cell lysate/extract. 12 % SDS-PAGE. Livin antibody (TA308543) dilution: 1:500
IHC Image
Immunohistochemical analysis of paraffin-embedded Cal27 xenograft , using ML-IAP(TA308543) antibody at 1:100 dilution.
IF Image
Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using ML-IAP(TA308543) antibody at 1:200 dilution.

 

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