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Home Antibody All anti-BIRC5 antibodies

Anti-BIRC5 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA323465
  • Anti-BIRC5 rabbit polyclonal antibody
  • FREE positive control: HEK293T cell transient overexpression lysate (LC423314) , 20ug
100ul 325 2-3 Weeks
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WB(1)
IHC(1)
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Also for BIRC5 (NM_001012270)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenFull length fusion protein
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.9mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsELISA: 1:1000-5000, WB: 1:500-2000, IHC: 1:25-100
BufferPBS pH7.3, 0.05% NaN3, 50% glycerol
Purification Antigen affinity purification

Reference Data

Target NameHomo sapiens baculoviral IAP repeat containing 5 (BIRC5), transcript variant 2
Alternative NameAPI4; EPR-1
Database LinkNP_001012270
FunctionThis gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Related Pathway
Apoptosis
Cell cycle

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WB Image
Predicted band size: 16 kDa . Positive control: A431, Jurkat and Hela cell lysate. Recommended dilution: 1/500-2000. (Gel: 12%SDS-PAGE Lane 1: A431 cell lysate Lane 2: Jurkat cell lysate Lane 3: Hela cell lysate Lysates: 40 ug per lane Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 5 seconds)
IHC Image
Predicted cell location: Cytoplasm. Positive control: Human colon cancer tissue. Recommended dilution: 1/25-100 The image on the left is immunohistochemistry of paraffin-embedded human colon cancer tissue using BIRC5 antibody at dilution 1/25, on the right is treated with the fusion protein. (Original magnification:x200)

 

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