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Home Antibody All anti-BIRC5 antibodies

Anti-BIRC5 Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA323465 Anti-BIRC5 rabbit polyclonal antibody 100ul 325
2-3 Weeks
LC423314 BIRC5 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenFull length fusion protein
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.9mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsELISA: 1:1000-5000, WB: 1:500-2000, IHC: 1:25-100
Predicted MW Explanation 16kDa
BufferPBS pH7.3, 0.05% NaN3, 50% glycerol
Purification Antigen affinity purification

Reference Data

Target NameHomo sapiens baculoviral IAP repeat containing 5 (BIRC5), transcript variant 2
Alternative NameAPI4; EPR-1
Database LinkNP_001012270
Entrez Gene 332 Human
Entrez Gene 11799 Mouse
Entrez Gene 64041 Rat
FunctionThis gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Related PathwayStem cell - PluripotencyDruggable Genome Pathways in cancerColorectal cancer

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Predicted band size: 16 kDa . Positive control: A431, Jurkat and Hela cell lysate. Recommended dilution: 1/500-2000. (Gel: 12%SDS-PAGE Lane 1: A431 cell lysate Lane 2: Jurkat cell lysate Lane 3: Hela cell lysate Lysates: 40 ug per lane Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 5 seconds)

IHC Image
Predicted cell location: Cytoplasm. Positive control: Human colon cancer tissue. Recommended dilution: 1/25-100 The image on the left is immunohistochemistry of paraffin-embedded human colon cancer tissue using BIRC5 antibody at dilution 1/25, on the right is treated with the fusion protein. (Original magnification:x200)


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