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Home Antibody All anti-BIRC5 antibodies

Anti-BIRC5 Antibody

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SKU Description Amount Price Availability*  
TA323464
  • Anti-BIRC5 Rabbit Polyclonal Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC423314) , 20ug Explanation
100ul $325 2-3 Weeks
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WB(1)
IHC(1)

OriGene Data

ImmunogenFull length fusion protein
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.6mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsELISA: 1:1000-5000, WB: 1:200-1000, IHC: 1:10-50
Predicted MW Explanation 16kDa
BufferPBS pH7.3, 0.05% NaN3, 50% glycerol
Purification Antigen affinity purification

Reference Data

Target NameHomo sapiens baculoviral IAP repeat containing 5 (BIRC5), transcript variant 2
Alternative NameAPI4; EPR-1
Database LinkNP_001012270
Entrez Gene 332 Human
Entrez Gene 11799 Mouse
Entrez Gene 64041 Rat
FunctionThis gene is a member of the inhibitor of apoptosis (IAP) gene family; which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains; but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors; yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Related PathwayStem cell - PluripotencyDruggable Genome Pathways in cancerColorectal cancer

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of HepG2 and 231 cell using TA323464(BIRC5 Antibody) at dilution 1/300
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Immunohistochemistry of paraffin-embedded Human lung cancer tissue using TA323464(BIRC5 Antibody)(left image) at dilution 1/10, the image on the right is treated with the fusion protein.(Original magnification: x200)
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