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Home Antibody All anti-BIRC5 antibodies

Anti-BIRC5 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306025
  • Rabbit Polyclonal Survivin Antibody
  • FREE positive control: HEK293T cell transient overexpression lysate (LC425312) , 20ug
100ug 325 3-7 Days
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WB(1)
IF(1)
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Also for BIRC5 (NM_001012270)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenSurvivin antibody was raised against a peptide corresponding to amino acids near the amino terminus of human survivin.
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsELISA, WB: 1 - 2 ug/ml, ICC: 5 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens baculoviral IAP repeat containing 5 (BIRC5), transcript variant 2
Alternative NameAPI4; EPR-1
Database LinkNP_001012270
FunctionApoptosis, or programmed cell death, is related to many diseases, such as cancer. Apoptosis is triggered by a variety of stimuli including members in the TNF family and prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form a conserved gene family that binds to and inhibits cell death proteases. A novel IAP protein was recently identified and designated survivin, apoptosis inhibitor 4 (API4), and TIAP (1-3). Survivin/TIAP interacted with the processed form of caspase-3 and inhibited its proteolytic activity. Survivin/TIAP is predominantly expressed in tissues of embryos, transformed cell lines, and many human cancers and lymphomas .
Related Pathway
Apoptosis
Cell cycle

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WB Image
Western blot analysis of Survivin in MOLT4 cell lysate with Survivin antibody at (A) 1 and (B) 2 ug/mL.
IF Image
Immunocytochemistry of Survivin in Jurkat cells with Survivin antibody at 5 ug/mL.

 

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