The product of this gene is a member of the BAR domain protein family. The encoded protein is comprised solely of a BAR domain which is predicted to form coiled-coil structures and proposed to mediate dimerization, sense and induce membrane curvature, and bind small GTPases. BAR domain proteins have been implicated in endocytosis, intracellular transport, and a diverse set of other processes. [provided by RefSeq]. COMPLETENESS: complete on the 3' end.
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY BIN3 (RC203378, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-BIN3.
HEK293T cells transfected with either RC203378 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-BIN3 antibody(TA502145), and then analyzed by flow cytometry.
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