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Anti-BID Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA323206
  • Anti-BID Rabbit Polyclonal Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC420074) , 20ug
100ul 325 In Stock
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WB(1)
IHC(1)
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Also for BID (NM_001196)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFull length fusion protein
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1.2mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsELISA: 1:1000-5000, WB: 1:200-2000, IHC: 1:25-100
BufferPBS pH7.3, 0.05% NaN3, 50% glycerol
Purification Antigen affinity purification

Reference Data

Target NameHomo sapiens BH3 interacting domain death agonist (BID), transcript variant 2
Alternative NameFP497
Database LinkNP_001187
FunctionThis gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein; and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found; but the full-length nature of some variants has not been defined.
Related Pathway
Apoptosis

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Predicted band size: 22kDa. Positive control: Human fetal brain and liver tissue, HT-29 and HepG2 cell lysate. Recommended dilution: 1/200-2000. (Gel: 12%SDS-PAGE Lane1: Human fetal brain tissue lysate Lane2: Human fetal liver tissue lysate Lane3: HT-29 cell lysate Lane4: HepG2 cell lysate Lysates: 30 ug per lane Primary antibody: 1/260 dilution Secondary antibody: Donkey anti Rabbit IgG - H&L (HRP) at 1/3000 dilution Exposure time: 1minute)
IHC Image
Predicted cell location: Cytoplasm, Cell membrane. Positive control: Human renal cancer tissue. Recommended dilution: 1/25-100 The image on the left is immunohistochemistry of paraffin-embedded Human renal cancer tissue using BID antibody at dilution 1/25, on the right is treated with the fusion protein. (Original magnification: x100)

 

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