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Home Antibody All anti-BGLAP antibodies

Anti-BGLAP Antibody EPR3690

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA310210 Rabbit Monoclonal antibody against Osteocalcin (BGLAP) 100ul $325 In Stock
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WB(1)
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Also for BGLAP (NM_199173)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Osteocalcin was used as an immunogen.
Clone NameEPR3690 IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:1000 - 1:10000
BufferpH: 7.20; Preservative: 0.01% Sodium azide; Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Note Is unsuitable for IHC-P or IP.

Reference Data

Target NameHomo sapiens bone gamma-carboxyglutamate (gla) protein (BGLAP)
Alternative NameBGP; OC; OCN
Database LinkNP_954642
Entrez Gene 632 Human
FunctionOsteocalcin, a vitamin K-dependent protein, constitutes 1-2% of total bone protein, and it binds strongly to apatite and calcium (1, 2). Thus, Osteocalcin is involved in bone extracellular matrix mineralization and bone formation (2, 3). Moreover, it exists in serum as fully carboxylated or partially carboxylated forms and completely uncarboxylated. Uncarboxylated Osteocalcin promotes insulin secretion, insulin gene expression and insulin sensitivity (4). In addition, it acts as a hormone with a complex cross-talk between adipose tissue and the skeleton (3).
Related PathwaySecreted ProteinES Cell Differentiation/IPS

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - Anti-Osteocalcin antibody; Anti-Osteocalcin [EPR3690] antibody at 1/1000 dilution + Human Osteocalcin recombinant protein at 0.01 ug.Predicted band size : 11 kDa.
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