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Home Antibody All anti-BDKRB2 antibodies

Anti-BDKRB2 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA321167
  • Anti-BDKRB2 rabbit polyclonal antibody
100ul 325 2-3 Weeks
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WB(1)
IHC(1)

OriGene Data

ImmunogenSynthetic peptide corresponding to a region derived from 377-391 amino acids of human bradykinin receptor B2
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1.1mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsELISA: 1:2000-5000, WB: 1:200-1000, IHC: 1:50-200
Predicted MW Explanation 44kDa
BufferPBS pH7.3, 0.05% NaN3, 50% glycerol
Purification Antigen affinity purification

Reference Data

Target NameHomo sapiens bradykinin receptor B2 (BDKRB2)
Alternative NameB2R; BK-2; BK2; BKR2; BRB2
Database LinkNP_000614
Entrez Gene 624 Human
Entrez Gene 12062 Mouse
Entrez Gene 25245 Rat
FunctionThis gene encodes a receptor for bradykinin. The 9 aa bradykinin peptide elicits many responses including vasodilation, edema, smooth muscle spasm and pain fiber stimulation. This receptor associates with G proteins that stimulate a phosphatidylinositol-calcium second messenger system. Alternate start codons result in two isoforms of the protein.
Related PathwayGPCRTransmembraneDruggable Genome Calcium signaling pathwayNeuroactive ligand-receptor interactionComplement and coagulation cascadesRegulation of actin cytoskeleton

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Predicted band size: 44kDa. Positive control: Human leiomyosarcoma tissue and NIH/3T3 cell lysate. Recommended dilution: 1/200-1000. (Gel: 10%SDS-PAGE Lane1: Human leiomyosarcoma tissue lysate Lane2: NIH/3T3 cell lysate Lysates: 50 ug per lane Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/8000 dilution Exposure time: 1 minute)
IHC Image
Predicted cell location: Cytoplasm. Positive control: Human ovarian cancer tissue . Recommended dilution: 1/50-200 The image on the left is immunohistochemistry of paraffin-embedded human ovarian cancer tissue using BDKRB2 antibody at dilution 1/30, on the right is treated with the synthetic peptide. (Original magnification:x200)

 

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