Home Antibody All anti-BDKRB1 antibodies
Also for BDKRB1 (NM_000710)
|Peptide with sequence KVWELYKQCTPK, from the internal region of the protein sequence according to NP_000701.2.|
|Test: Human. Expected from seq similarity: Human
||Lot dependent; please refer to CoA along with shipment
||ELISA: 1:1,000. WB: 2-4µg/ml.
|Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.|
|Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
|Homo sapiens bradykinin receptor B1 (BDKRB1)|
|B1BKR; B1R; BDKRB2; BKB1R; BKR1; BRADYB1|
|Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. The protein encoded by this gene is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses. [provided by RefSeq]. |
Signaling by GPCR
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TA302436 (2µg/ml) staining of K562 lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.