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Home Antibody All anti-BCR antibodies

Anti-BCR Antibody Polyclonal

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA303402
  • Rabbit polyclonal antibody against Bcr (C-term)(Polyclonal )
100ul 379 3-7 Days
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WB(1)
IHC(1)
IF(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in the C-term of human Bcr was used as immunogen.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC, IF Suggested DilutionsIHC: 1:100-250; ICC: 1:250-500; IP: 1:40
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Protein A purified
Note Does not react with Mouse, Rat

Reference Data

Target NameHomo sapiens breakpoint cluster region (BCR), transcript variant 1
Alternative NameALL; BCR1; CML; D22S11; D22S662; PHL
Database LinkNP_004318
FunctionA reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Related Pathway

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WB Image
Western blot - Anti-Bcr antibody; Anti-Bcr antibody at 1/40 dilution + immunoprecipitation pellets from Jurkat cell lysate .Observed band size : 130 kDa .
IHC Image
Immunohistochemistry (Paraffin-embedded sections) - Bcr antibody; Immunohistochemical analysis of paraffin-embedded human lung carcinoma using TA303402 at 1/100 dilution.
IF Image
Immunocytochemistry/ Immunofluorescence - Bcr antibody; Immunofluorescent staining of HeLa cells using TA303402 at 1/250 dilution.

 

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