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Anti-BCL6 TRUEMAB Antibody Clone OTI6C7

TrueMAB™ Antibodies - Made against Authentic Protein Antigens


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA803402 Purified BCL6 mouse monoclonal antibody, clone OTI6C7 (formerly 6C7) 100ul 325
In Stock
LC400639 BCL6 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF803402 Carrier-free (BSA/glycerol-free) BCL6 mouse monoclonal antibody, clone OTI6C7 (formerly 6C7) 100ug $450 3 Days
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OriGene Data

ImmunogenHuman recombinant protein fragment corresponding to amino acids 1-300 of human BCL6 (NP_001697) produced in E.coli.
Clone NameClone OTI6C7 IsotypeIgG1
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application *WB Suggested Dilutions WB 1:2000,
Predicted MW Explanation 78.7 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens B-cell CLL/lymphoma 6 (BCL6), transcript variant 1
Alternative NameBCL5; BCL6A; LAZ3; ZBTB27; ZNF51
Database LinkNP_001697
Entrez Gene 604 Human
FunctionThe protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of START-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Sep 2008].
Related PathwayTranscription FactorsDruggable Genome

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* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY BCL6 (RC219007, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-BCL6.


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