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Home Antibody All anti-BCL6 antibodies

Anti-BCL6 Antibody EP529Y

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA300570
  • Rabbit Monoclonal Antibody against BCL6 (Clone EP529Y)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400639) , 20ug Explanation
100ul 325 In Stock
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WB(1)
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Also for BCL6 (NM_001706)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in the C-term of human Bcl-6 was used as immunogen.
Clone NameEP529Y IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsIP: 1:50; WB: 1:500 - 1:2000; ICC: 1:100 - 1:250; ICC/IF: Use at an assay dependent concentration; IHC-P: Use at an assay dependent concentration
BufferDoes not react with Mouse, Rat. Is unsuitable for Flow Cyt.
Purification PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt.

Reference Data

Target NameHomo sapiens B-cell CLL/lymphoma 6 (BCL6), transcript variant 1
Alternative NameBCL5; BCL6A; LAZ3; ZBTB27; ZNF51
Database LinkNP_001697
Entrez Gene 604 Human
FunctionBcl-6 (also known as LAZ3) is a member of the POZ/zinc finger (POK) family that contains an N-terminal POZ domain and 6 C-terminal zinc finger motifs (1). Bcl-6 is a transcriptional regulator that plays an important role in lymphocyte, myocyte, male germ cells, and keratinocyte survival and or differentiation (2-3). Bcl-6 has also been found to repress a number of genes involved in B cell activation and terminal differentiation, inflammation and cell cycle regulation (4). Chromosomal aberration in Bcl-6 may be a cause of B-cell non –Hodgkin lymphoma and B-cell leukemia (5).
Related PathwayTranscription FactorsDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Bcl6 antibody [EP529Y]; Anti-Bcl6 antibody [EP529Y] at 1/2000 dilution + Daudi cell lysate.Predicted band size : 78 kDa.Observed band size : 85-90 kDa .

 

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