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Home Antibody All anti-BCL2L2 antibodies

Anti-BCL2L2 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA324130
  • Anti-BCL2L2 Rabbit Polyclonal Antibody
100ul $325 2-3 Weeks
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IHC(2)
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Also for BCL2L2 (NM_004050)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFusion protein corresponding to a region derived from 1-188 amino acids of human BCL2-like 2
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.5mg/ml
Guaranteed Application *IHC Suggested DilutionsELISA: 1:1000-2000, IHC: 1:15-50
BufferPBS pH7.3, 0.05% NaN3, 50% glycerol
Purification Antigen affinity purification

Reference Data

Target NameHomo sapiens BCL2-like 2 (BCL2L2), transcript variant 1
Alternative NameBCL-W; BCL2-L-2; BCLW; PPP1R51
Database LinkNP_004041
FunctionThis gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream PABPN1 (poly(A) binding protein, nuclear 1) gene.?
Related Pathway
Apoptosis

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IHC Image
Predicted cell location: Cytoplasm. Positive control: Human gastric and liver cancer tissue. Recommended dilution: 1/15-50 The image on the left is immunohistochemistry of paraffin-embedded human gastric cancer tissue using BCL2L2 antibody at dilution 1/15, on the right is treated with the fusion protein. (Original magnification:x 200)
IHC Image
Predicted cell location: Cytoplasm. Positive control: Human gastric and liver cancer tissue. Recommended dilution: 1/15-50 The image on the left is immunohistochemistry of paraffin-embedded human liver cancer tissue using BCL2L2 antibody at dilution 1/15, on the right is treated with the fusion protein. (Original magnification:x200)

 

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