OriGene Technologies, Inc.
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-BCL2L1 antibodies

Anti-BCL2L1 TRUEMAB Antibody clone 4A9

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

div

Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA500097
  • anti-Bcl-XL mouse monoclonal antibody,clone 4A9
  • FREE positive control: HEK293T cell transient overexpression lysate (LC403363) , 20ug
100ul
30ul
$379 In Stock
CF500097
  • Carrier-free (BSA/glycerol-free) Bcl-XL mouse monoclonal antibody,clone 4A9
100ug $450 3-4 weeks
Add to Shopping Cart
WB(1)
IF(2)
spacer
Also for BCL2L1 (NM_138578)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenRecombinant fragment expressed in E.coli corresponding to amino acids 1-212 of human Bcl-XL
Clone Nameclone 4A9 IsotypeIgG2a
Species ReactivityHuman Concentration0.25mg/ml
Guaranteed Application *WB, IF Suggested DilutionsWB: 1:500, IF (1:100)
BufferPBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Reference Data

Target NameHomo sapiens BCL2-like 1 (BCL2L1), transcript variant 1
Alternative NameBcl-X; bcl-xL; BCL-XL/S; bcl-xS; BCL2L; BCLX; BCLXL; BCLXS; PPP1R52
Database LinkNP_612815
FunctionBcl-XL belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported. The longer isoform acts as an apoptotic inhibitor and the shorter form acts as an apoptotic activator
Related Pathway
Apoptosis
Jak-STAT signaling pathway

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY BCL2L1(RC201314) (RC201314, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-BCL2L1.
IF Image
Anti-BCL2L1 mouse monoclonal antibody (TA500097) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY BCL2L1(RC201314).
IF Image
Immunofluorescent staining of HT29 cells using anti-BCL2L1 mouse monoclonal antibody (TA500097).

 

spacer
Inc 5000 Healthcare Company Copyright © 2014 OriGene Technologies, Inc. All Rights Reserved. Legal Notices.
9620 Medical Center Dr., Suite 200, Rockville, MD 20850 • 1.888.267.4436

Reproduction of any materials from this website is strictly forbidden without permission.

All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title