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Home Antibody All anti-BCL2A1 antibodies

Anti-BCL2A1 Antibody EP517Y


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA303401 Rabbit monoclonal antibody against Bcl-2 related protein A1/Bfl1 (N-term) (EP517Y) 100ul $325 In Stock
LC418253 BCL2A1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues in the N-term of human Bcl-2 related protein A1 was used as immunogen.
Clone NameEP517Y IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC, IF, FC Suggested DilutionsICC/IF: 1:100 - 1:250; WB: 1:500; IHC-P: Use at an assay dependent dilution; FC: 1:100
Predicted MW Explanation 20 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification IgG fraction
Note Is unsuitable for IP.

Reference Data

Target NameHomo sapiens BCL2-related protein A1 (BCL2A1), transcript variant 1
Alternative NameACC-1; ACC-2; ACC1; ACC2; BCL2L5; BFL1; GRS; HBPA1
Database LinkNP_004040
Entrez Gene 597 Human
Entrez Gene 170929 Rat
FunctionThis gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and is up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Related PathwayDruggable Genome Metabolic pathways

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - A1 antibody [EP517Y]; Anti-Bcl2A1 antibody [EP517Y] at 1/500 dilution + Raji cell lysate.Predicted band size : 20 kDa.Observed band size : 27 kDa .
Immunohistochemistry (Paraffin-embedded sections) - A1 antibody [EP517Y]; TA303401, at a 1/50 dilution, staining human adenocarcinoma by Immunohistochemistry, Paraffin embedded tissue.
Immunocytochemistry/ Immunofluorescence - Bcl2A1 antibody [EP517Y]; TA303401 at 1/100, staining Hela cell lysate by Immunofluorescent.
Flow Cytometry - Bcl2A1 antibody; Overlay histogram showing HepG2 cells stained with TA303401 (red line). The secondary antibody used was DyLight 488 goat anti-rabbit IgG (H+L) at 1:500. Isotype control antibody (black line) was rabbit IgG (monoclonal) (1ug/1x10^6 cells) used under the same conditions. Acquisition of >5,000 events was performed.


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