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Home Antibody All anti-BCL10 antibodies

Anti-BCL10 Antibody EPR3175

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307332
  • Rabbit monoclonal antibody against Bcl-10(clone EPR3175)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC418351) , 20ug
100ul $325 3-7 Days
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WB(1)
IF(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human EN1 was used as an immunogen.
Clone NameEPR3175 IsotypeTissue culture supernatant
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IF Suggested DilutionsICC/IF: 1:100 - 1:250; WB: 1:1000 - 1:10000; IP: 1:10 - 1:100
BufferDoes not react with Mouse, Rat. Is unsuitable for Flow Cyt or IHC-P.
Purification PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt or IHC-P.

Reference Data

Target NameHomo sapiens B-cell CLL/lymphoma 10 (BCL10)
Alternative Namec-E10; CARMEN; CIPER; CLAP; mE10
Database LinkNP_003912
FunctionBcl-10 is an adaptor protein with a caspase recruitment domain (CARD) that promotes apoptosis and activates pro-caspase 9 and NF-kB (1, 2). Bcl-10 also interacts with other CARD domain containing proteins including CARD9, 10, 11 and 14. Bcl-10 is found to form a complex with MALT1, a protein known to be translocated in MALT lymphomas. Bcl-10 and MALT1 play a critical role in antigen receptor-mediated lymphocyte proliferation and signaling to NF-B, which controls the expression of genes critical for cell survival, proliferation, and immune responses (3,4). Defects in Bcl-10 have been identified in various types of cancer.
Related Pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Bcl10 antibody [EPR3175]; All lanes : Anti-Bcl10 antibody [EPR3175] at 1/1000 dilution.Lane 1 : Daudi cell lysate.Lane 2 : Raji cell lysate.Lane 3 : HeLa cell lysate.Lane 4 : HuT-78 cell lysate.Lysates/proteins at 10 µg per lane.Predicted band size : 26 kDa.
IF Image
Immunocytochemistry/ Immunofluorescence - Bcl10 antibody [EPR3175]; TA307332, at 1/100 dilution, staining Bcl10 in HeLa cells by Immunofluorescence.

 

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